Poloxamer L64 & L65 Polyethylene Polypropylene Glycol
CAS 9003-11-6 Propylene Glycol Block Polyether
L64 / L65 Polyethylene-polypropylene glycol
Also known as Synperonic pe(R) / Poloxamer
Chemical composition: Propylene Glycol Block Polyether
L64 Polyethylene Polypropylene Glycol
Used for manufacturing low-foam detergents or defoamers. L64 is employed in preparing synthetic detergents with low foam and high detergency properties. Applications include:
- Pesticide emulsifiers
- Coolants and lubricants in metal cutting and grinding
- Lubricant for rubber vulcanization
- Preventing hard scale formation in oil pipelines
- Secondary oil recovery processes
| Model Number |
L64 |
| Appearance (25℃) |
Milky white paste |
| Molecular Weight |
2900 |
| Viscosity (25ºC CPS) |
550 |
| Cloud Point (1% aqueous solution) |
57~61 |
| Moisture (%) |
≤ 1.0 |
| pH Value (1% aqueous solution) |
5.0~7.0 |
| HLB Value |
13 |
L65 Polyethylene Polypropylene Glycol
Primarily used in the wool spinning industry as a wool protective agent. Adding approximately 0.3% during the wool carbonization process provides significant benefits:
- Reduces wool scale damage
- Enhances single fiber strength by 10%
- Reduces spinning end breakage rate by 10%
| Model Number |
L65 |
| Appearance (25℃) |
Milky white paste |
| Molecular Weight |
3500 |
| Cloud Point (1% aqueous solution) |
75~85 |
| Moisture (%) |
≤ 1.0 |
| pH Value (1% aqueous solution) |
5.0~7.0 |
| HLB Value |
15 |
Packaging and Storage
Package: 1000Kg/IBC drum or 200Kg/drum (Net weight)
Storage and Transportation: Store and transport as general chemicals. Keep in a dry and ventilated place.
Shelf Life: Two years
Performance and Applications
1. As an Emulsifier and Stabilizer
Poloxamer is one of the few synthetic emulsifiers used in intravenous emulsions as a water-in-oil emulsifier. Dosage: 0.1% to 5%. The emulsion prepared with this product features:
- Smaller milk particles (typically below 1μm)
- High absorption rate
- Stable physical properties resistant to autoclave sterilization and low-temperature freezing
2. As a Solubility Enhancer
This product increases the surface solubility of various drugs (salicylic acid, indomethacin, metronidazole) through micelle formation. Example: Salicylic acid solubility in Pluronic L65 and F68 demonstrates stable solubility across different concentrations.
3. As an Absorption Enhancer
Dual mechanism: slows intestinal peristalsis to prolong drug retention time and improve bioavailability of oral formulations; enhances skin permeability for topical applications due to excellent skin compatibility.
4. As Sustained-Release Materials
High molecular weight solid products serve as adhesives, coating materials for tablets, capsules, and gels to achieve controlled release. Dosage: 5% to 15%.
Technical Information
| Name |
Appearance (25ºC) |
Average Molecular Weight |
Viscosity (25ºC CPS) |
Cloud Point 1% |
Moisture (%) |
pH Value |
HLB Value |
| L31 |
Colorless transparent liquid |
1100 |
200 |
37 |
≤ 1.0 |
5.0~7.0 |
3.5 |
| L35 |
Milky white paste |
1900 |
320 |
70~85 |
≤ 1.0 |
5.0~7.0 |
18.5 |
| F38 |
White solid |
5000 |
- |
>100 |
≤ 1.0 |
5.0~7.0 |
30 |
| L42 |
Colorless transparent liquid |
1630 |
250 |
37 |
≤ 1.0 |
5.0~7.0 |
8 |
| L43 |
- |
1850 |
310 |
42 |
≤ 1.0 |
5.0~7.0 |
10 |
| L44 |
- |
2200 |
440 |
45~55 |
≤ 1.0 |
5.0~7.0 |
12 |
| L45 |
Colorless liquid to paste |
2400 |
- |
75~85 |
≤ 1.0 |
5.0~7.0 |
15 |
| L61 |
Colorless transparent liquid |
2000 |
285 |
17~21 |
≤ 1.0 |
5.0~7.0 |
3 |
| L62 |
- |
2500 |
400 |
21~26 |
≤ 1.0 |
5.0~7.0 |
7 |
| L63 |
Colorless liquid to paste |
2650 |
475 |
34 |
≤ 1.0 |
5.0~7.0 |
11 |
| L64 |
Milky white paste |
2900 |
550 |
57~61 |
≤ 1.0 |
5.0~7.0 |
13 |
| L65 |
- |
3500 |
- |
75~85 |
≤ 1.0 |
5.0~7.0 |
15 |
| F68 |
White flaky solid |
8350 |
- |
>100 |
≤ 1.0 |
5.0~7.0 |
29 |
Frequently Asked Questions
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About Us
Lihong Technology continues to increase investment in advanced safety and environmental protection facilities. As a second-level enterprise for production safety standardization, many products have passed food-grade certification.
The company adheres to quality as its foundation, operating advanced quality management and information management systems to enhance product quality process control. Relying on advanced technology and equipment, we actively create world-class product quality and corporate image.
Leading high-quality development through technological innovation, we employ over 30 high-end industry professionals and maintain three R&D platforms: Jiangsu Technology R&D Center, Jiangsu Polyurethane New Material Engineering Technology Research Center, and Jiangsu Special Polyurethane New Material Engineering Research Center.
With 5 invention patents, 22 utility model patents, and over 10 pending invention patents, our specific functional flame-retardant polyether polyols have been identified as a key R&D project in Huai'an City.
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